Cholesteryl pullulan
WebMar 25, 2011 · Cholesteryl group-bearing pullulan complexed with the truncated HER-2 protein, delivered a HER-2 oncoprotein containing an epitope peptide to the major histocompatibility complex class I pathway, and was able to induce CD8+ cytotoxic T lymphocytes against HER-2+ tumors and caused complete rejection of tumors.
Cholesteryl pullulan
Did you know?
WebFeb 1, 2015 · Request PDF On Feb 1, 2015, Ram Sarup Singh and others published Pullulan and pullulan derivatives as promising biomolecules for drug and gene targeting Find, read and cite all the research ... WebExpert opinion: The most advanced models of nanogel-based vaccines comprise candidates against cancer, based on cholesteryl pullulan nanogels evaluated in clinical trials with promising findings; as well as some vaccines against respiratory pathogens tested in …
WebDec 6, 2012 · Self-assembled protein-loaded pH-sensitive cholesteryl pullulan-based nanogels were developed to retain the encapsulated protein at the physiological … WebOct 29, 2009 · However, there are no standard therapies established for recurrent esophageal cancer. NY-ESO-1 antigen is expressed in 33% of patients. NY-ESO-1 protein is applicable without limitation by HLA types, and injected as a complex with cholesteryl pullulan (CHP), forming nano-particles (IMF-001), it can activate both CD4+ and CD8+ …
WebTo create a drug delivery system that allows the controlled release of proteins, such as growth factors, over a long-term period, cholesteryl group- and acryloyl group-bearing pullulan (CHPOA) nanogels were aggregated to form fast-degradable hydrogels (CHPOA/hydrogels) by cross-linking with thiol-bearing polyethylene glycol. WebApr 11, 2024 · The obtained cholesteryl-hyaluronic acid-drug compounds were rapidly shaped into compressed NG with a size of 50 nm with the help of ultrasonication [60]. The method of developing hydrophobic cholesterol-altered amino-pullulan (CHAP) compounds from pullulan that has been grafted with hydrophobic groups and ethylenediamine is …
WebCholesteryl pullulan (CHP) is a novel antigen delivery system. CHP and New York esophageal squamous cell carcinoma 1 (NY-ESO-1) antigen complexes (CHP-NY-ESO-1) present multiple epitope peptides to the MHC class I and II pathways. Adjuvants are essential for cancer vaccines.
WebPullulan is mainly used by the cell to resist desiccation and predation. The presence of this polysaccharide also facilitates diffusion of molecules both into and out of the cell. The … skin reaction to salicylic acidWebDec 25, 2024 · Pullulan has been progressively defined as base-producing material of gene and drug nanocarriers. The most popular feature of these nanocarriers is the utilization of hydrophobic derivatives of pullulan, like cholesteryl-pullulan since this produces an amphiphilic pullulan derivative with the ability to form nanoparticles by self-aggregation. skin reaction to soapWebJun 20, 2010 · A nanometre-sized hydrogel consisting of a cationic type of cholesteryl group bearing pullulan has now been used as an intranasal vaccine-delivery system. swansboro vacations packagesWebJan 8, 2024 · Fujioka-Kobayashi et al. studied the combination of FGF-18 with the bone morphogenic protein (BMP)-2 and found it was sufficient at showing significant bone regeneration potential in crosslinked acrylol cholestrol modified pullulan nanogels. These factors were combined with stimulated thick trabecular bone formation . Charoenlarp et … swansboro west richmond va crimeWebOVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1 … skin reaction to shampooWebAbstract. In this study, a novel nanoparticulate drug delivery platform with inherent targeting ability to hepatic carcinoma cells and reduction-triggered drug release … swansboro vet clinicWebOct 5, 2013 · Background: Cholesteryl pullulan (CHP) is a novel antigen delivery system for cancer vaccines. This study evaluated the safety, immune responses and clinical … swansboro veterinary clinic